By which 'sense' are you most affected?

All of them!  Visual is extremely important to me as I cannot imagine not being able to enjoy the beauty of the sky, sunsets, clouds or the diversity in nature and smiles! :)  I also tremendously enjoy art of all types.  On the other hand, I cannot imagine living without music for it connects all of humanity at a deep level.  There is never a day when I do not listen to music.  Then there is the enjoyment of hearing the birds sing, the ocean waves, the animals talk.  Being a touchy-feely person, I rely on close physical contact/hugs with my friends, and animals, as well as enjoy the feeling of beautiful fabrics, stones, trees, anything with texture.  So all in all, I guess I could say that there is not one of the five senses that is more important to me than the other.

Of course these have their negative components as well--the sights and sounds of war, grief, poverty, not to mention the physical violence of rape and secual abuse that occurs among people.  Any of them affects me to the point of also touching my soul in a way that my heart aches for humanity.  But, I choose to focus on the beauty................